polymyxin M
- Norine ID: NOR01062
- DOI: 10.26097/nor01062
- Family: polymyxin
- Synonym(s): polymyxin M;
- Activity: antimicrobial
- Category: lipopeptide
- Formula: C51H97N16O14
- Monoisotopic mass: 1157.737016892 g/mol
- Comment: It contain 6-methyloctanoicacid
- Source: norine
- Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
- Entry information:
- status: curated - change status to non-NRP (Norine validators only)
- last modification date: 2018-12-01 by Emma Ricart Altimiras [Swiss Institute of Bioinformatics, SIB]
- view all entry history
- Type: partial cyclic
- Number of monomers: 11
- Smiles: CCC(C)CCCCC(=O)NC(CCN)C(=O)NC(C(C)O)C(=O)NC(CCN)C(=O)NC1CCNC(=O)C(NC(=O)C(CCN)NC(=O)C(CCN)NC(=O)C(NC(=O)C(CC(C)C)NC(=O)C(CCN)NC1(=O))C(C)O)C(C)O
- Graph inference:
- Monomeric composition :
1 aC9:0 2 Dab 3 Thr 4 Dab 5 Dab 6 Dab 7 D-Leu 8 Thr 9 Dab 10 Dab 11 Thr - Graph representation: aC9:0,Dab,Thr,Dab,Dab,Dab,D-Leu,Thr,Dab,Dab,Thr @1 @0,2 @1,3 @2,4 @3,5,10 @4,6 @5,7 @6,8 @7,9 @8,10 @4,9
- Atomic structure:


- Paenibacillus kobensis
- gram: positive
- synonyms: Bacillus kobensis
- taxid: 59841 (view NCBI taxonomy browser)
- Links between organisms producing the polymyxin M: Paenibacillus kobensis
- Isolation, structural characterization, and properties of mattacin (polymyxin M), a cyclic peptide antibiotic produced by Paenibacillus kobensis M
Churey JJ, Worobo RW, Martin NI, Hu H, Moake MM, Whittal R, Vederas JC, The Journal of biological chemistry , 2003, Apr 11,278(15):13124-32.
DOI: 10.1074/jbc.M212364200
pubMed: 12569104
