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viridogrisein


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  • Norine ID: NOR00672
  • DOI: 10.26097/nor00672
  • Family: neoviridogrisein
  • Synonym(s): viridogrisein;
  • Activity: antimicrobial
  • Category: peptide
  • Formula: C44H62N8O11
  • Monoisotopic mass: 878.453804866 g/mol
  • Comment: Etamycin is a putative NRPS product (no synthetase genes identified).
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
  • Type: partial cyclic
  • Number of monomers: 8
  • Smiles: CC(C)CC3NC(=O)C(NC(=O)c1ncccc1(O))C(C)OC(=O)C(c2ccccc2)N(C)C(=O)C(C)NC(=O)C(C(C)C(C)C)N(C)C(=O)CN(C)C(=O)C4CC(O)CN4(C3(=O))

  • Graph inference:



  • Monomeric composition :
    1
    Hpa
    2
    Thr
    3
    NMe-Ph-Gly
    4
    Ala
    5
    NMe-bMe-Leu
    6
    NMe-Gly
    7
    D-4OH-Pro
    8
    D-Leu
  • Graph representation: Hpa,Thr,NMe-Ph-Gly,Ala,NMe-bMe-Leu,NMe-Gly,D-4OH-Pro,D-Leu @1 @0,2,7 @1,3 @2,4 @3,5 @4,6 @5,7 @1,6

  • Atomic structure:
    • Chemical structure
    rBAN vizualisation:
  • Streptomyces
  • gram: positive
  • synonyms: Chainia
  • taxid: 1883 (view NCBI taxonomy browser)

  • Streptomyces griseus
  • gram: positive
  • synonyms: Actinomyces griseus
  • taxid: 1911 (view NCBI taxonomy browser)

  • Links between organisms producing the viridogrisein: Streptomyces, Streptomyces griseus
  • Purification and initial characterization of proline 4-hydroxylase from Streptomyces griseoviridus P8648: a 2-oxoacid, ferrous-dependent dioxygenase involved in etamycin biosynthesis
    Baldwin JE, Sobey WJ, Schofield CJ, Lawrence CC, Field RA, The Biochemical journal , 1996, Jan 1,313 ( Pt 1):185-91.
    DOI: 10.1042/bj3130185
    pubMed: 8546682


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