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polymyxin B6


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  • Norine ID: NOR01067
  • DOI: 10.26097/nor01067
  • Family: polymyxin
  • Synonym(s): polymyxin B6;
  • Activity: antimicrobial
  • Category: lipopeptide
  • Formula: C56H98N16O14
  • Monoisotopic mass: 1218.744841924 g/mol
  • Comment: Polymyxin B is a mixture of 6 components that differ on their fatty acid moety.
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
  • Type: partial cyclic
  • Number of monomers: 11
  • Smiles: CCC(C)CCC(O)CC(=O)NC(CCN)C(=O)NC(C(C)O)C(=O)NC(CCN)C(=O)NC2CCNC(=O)C(NC(=O)C(CCN)NC(=O)C(CCN)NC(=O)C(CC(C)C)NC(=O)C(Cc1ccccc1)NC(=O)C(CCN)NC2(=O))C(C)O

  • Graph inference:



  • Monomeric composition :
    1
    aC9:0-OH(3)
    2
    Dab
    3
    Thr
    4
    Dab
    5
    Dab
    6
    Dab
    7
    D-Phe
    8
    Leu
    9
    Dab
    10
    Dab
    11
    Thr
  • Graph representation: aC9:0-OH(3),Dab,Thr,Dab,Dab,Dab,D-Phe,Leu,Dab,Dab,Thr @1 @0,2 @1,3 @2,4 @3,5,10 @4,6 @5,7 @6,8 @7,9 @8,10 @4,9

  • Atomic structure:
  • Chemical structure
    rBAN vizualisation:
  • Bacillus polymyxa
  • gram: positive
  • synonyms: Paenibacillus polymyxa,Aerobacillus polymyxa,Granulobacter polymyxa,Clostridium polymyxa
  • taxid: 1406 (view NCBI taxonomy browser)

  • Links between organisms producing the polymyxin B6: Bacillus polymyxa
  • Characterization of polypeptide antibiotics of the polymyxin series by liquid chromatography electrospray ionization ion trap tandem mass spectrometry
    Govaerts C, Orwa J, Van Schepdael A, Roets E, Hoogmartens J, Journal of peptide science , 2002, Feb,8(2):45-55.
    DOI: 10.1002/psc.367
    pubMed: 11860028


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