apramide G
- Norine ID: NOR00411
- DOI: 10.26097/nor00411
- Family: apramide
- Synonym(s): apramide G;
- Activity: antitumor, toxin
- Category: lipopeptide
- Formula: C44H74N7O6S
- Monoisotopic mass: 828.5421288350001 g/mol
- Comment: Apramides are putative NRPS products (no synthetase genes identified).
- Source: norine
- Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
- Entry information:
- status: putative - change status to non-NRP (Norine validators only)
- last modification date: 2018-12-01 by Emma Ricart Altimiras [Swiss Institute of Bioinformatics, SIB]
- view all entry history
- Type: linear
- Number of monomers: 8
- Smiles: C[C@H](CCCCC#C)C(=O)N(C)[C@@H](C)C(=O)N(C)[C@@H](C(C)C)C(=O)N(C)[C@@H](C(C)C)C(=O)N(C)[C@@H](C(C)C)C(=O)N(C)[C@@H](C(C)C)C(=O)N1CCC[C@H]1C2=NC=CS2
- Graph inference:
- Monomeric composition :
1 C8:0:1(7)-Me(2) 2 NMe-Ala 3 NMe-Val 4 NMe-Val 5 NMe-Val 6 NMe-Val 7 NMe-Val 8 Pro-Thz - Graph representation: C8:0:1(7)-Me(2),NMe-Ala,NMe-Val,NMe-Val,NMe-Val,NMe-Val,NMe-Val,Pro-Thz @1 @0,2 @1,3 @2,4 @3,5 @4,6 @5,7 @6
- Atomic structure:
- Lyngbya majuscula
- gram: negative
- taxid: 158786 (view NCBI taxonomy browser)
- Links between organisms producing the apramide G: Lyngbya majuscula
- Apramides A-G, novel lipopeptides from the marine cyanobacterium Lyngbya majuscula
Luesch H, Moore RE, Paul VJ, Yoshida WY, Journal of natural products , 2000, Aug,63(8):1106-12.
DOI: 10.1021/np000078t
pubMed: 10978206
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