harzianin HC VIII
- Norine ID: NOR00991
- DOI: 10.26097/nor00991
- Family: harzianin
- Synonym(s): harzianin HC VIII;
- Activity: antimicrobial
- Category: peptaibol
- Formula: C68H117N15O16
- Monoisotopic mass: 1399.880272771 g/mol
- Source: norine
- Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
- Entry information:
- status: curated - change status to non-NRP (Norine validators only)
- last modification date: 2018-12-01 by Emma Ricart Altimiras [Swiss Institute of Bioinformatics, SIB]
- view all entry history
- Type: linear
- Number of monomers: 14
- Smiles: CC[C@](C)(C(=O)N[C@@H](CC(C)C)C(=O)NC(C)(C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)CO)NC(=O)[C@@H]2CCCN2C(=O)C(C)(C)NC(=O)[C@H](C(C)C)NC(=O)[C@H](C)NC(=O)[C@@H]3CCCN3C(=O)C(C)(C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(=O)N)NC(=O)C(C)(C)NC(=O)C
- Graph inference:
- Monomeric composition :
1 Ac-Aib 2 Asn 3 Leu 4 Aib 5 Pro 6 Ala 7 Val 8 Aib 9 Pro 10 Ival 11 Leu 12 Aib 13 Pro 14 Leuol - Graph representation: Ac-Aib,Asn,Leu,Aib,Pro,Ala,Val,Aib,Pro,Ival,Leu,Aib,Pro,Leuol @1 @0,2 @1,3 @2,4 @3,5 @4,6 @5,7 @6,8 @7,9 @8,10 @9,11 @10,12 @11,13 @12
- Atomic structure:
- Trichoderma harzianum
- synonyms: Hypocrea lixii
- taxid: 5544 (view NCBI taxonomy browser)
- Links between organisms producing the harzianin HC VIII: Trichoderma harzianum
- Interaction of the 14-residue peptaibols, harzianins HC, with lipid bilayers: permeability modifications and conductance properties
Rebuffat S, Goulard C, Bodo B, Lucaciu M, Duclohier H, Molle G, Biochimica et biophysica acta , 1997, Jan 14,1323(1):85-96.
DOI: 10.1016/s0005-2736(96)00179-4
pubMed: 9030215
- ANTIBIOTIC PEPTIDES FROM TRICHODERMA HARZIANUM: HARZIANINS HC, PROLINE-RICH 14-RESIDUE PEPTAIBOLS
Rebuffat S, Goulard C, Bodo B, Journal of the Chemical Society. Perkin transactions , 1995, no14,??pp.??1849-1855
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