harzianin HC VI
- Norine ID: NOR00990
- DOI: 10.26097/nor00990
- Family: harzianin
- Synonym(s): harzianin HC VI;
- Activity: antimicrobial
- Category: peptaibol
- Formula: C67H115N15O16
- Monoisotopic mass: 1385.8646227069999 g/mol
- Source: norine
- Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
- Entry information:
- status: curated - change status to non-NRP (Norine validators only)
- last modification date: 2018-12-01 by Emma Ricart Altimiras [Swiss Institute of Bioinformatics, SIB]
- view all entry history
- Type: linear
- Number of monomers: 14
- Smiles: C[C@@H](C(=O)N[C@@H](C(C)C)C(=O)NC(C)(C)C(=O)N1CCC[C@H]1C(=O)NC(C)(C)C(=O)N[C@@H](CC(C)C)C(=O)NC(C)(C)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CC(C)C)CO)NC(=O)[C@@H]3CCCN3C(=O)C(C)(C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(=O)N)NC(=O)C(C)(C)NC(=O)C
- Graph inference:
- Monomeric composition :
1 Ac-Aib 2 Asn 3 Leu 4 Aib 5 Pro 6 Ala 7 Val 8 Aib 9 Pro 10 Aib 11 Leu 12 Aib 13 Pro 14 Leuol - Graph representation: Ac-Aib,Asn,Leu,Aib,Pro,Ala,Val,Aib,Pro,Aib,Leu,Aib,Pro,Leuol @1 @0,2 @1,3 @2,4 @3,5 @4,6 @5,7 @6,8 @7,9 @8,10 @9,11 @10,12 @11,13 @12
- Atomic structure:
- Trichoderma harzianum
- synonyms: Hypocrea lixii
- taxid: 5544 (view NCBI taxonomy browser)
- Trichoderma viride strain NRRL 5243
- synonyms: Hypocrea rufa, Trichoderma lignorum
- Links between organisms producing the harzianin HC VI: Trichoderma harzianum, Trichoderma viride strain NRRL 5243
- Interaction of the 14-residue peptaibols, harzianins HC, with lipid bilayers: permeability modifications and conductance properties
Rebuffat S, Goulard C, Bodo B, Lucaciu M, Duclohier H, Molle G, Biochimica et biophysica acta , 1997, Jan 14,1323(1):85-96.
DOI: 10.1016/s0005-2736(96)00179-4
pubMed: 9030215
- ANTIBIOTIC PEPTIDES FROM TRICHODERMA HARZIANUM: HARZIANINS HC, PROLINE-RICH 14-RESIDUE PEPTAIBOLS
Rebuffat S, Goulard C, Bodo B, Journal of the Chemical Society. Perkin transactions , 1995, no14,??pp.??1849-1855
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