ampullosporin B
- Norine ID: NOR00938
- DOI: 10.26097/nor00938
- Family: ampullosporin
- Synonym(s): ampullosporin B;
- Activity: antimicrobial
- Category: peptaibol
- Formula: C76H125N19O19
- Monoisotopic mass: 1607.939912913 g/mol
- Comment: Peptaibol-type ampullosporins B and D are capable of forming ion-conducting pores in planar lipid bilayer membrane prepared from soybean phosphatidylcholine in a similar manner as it was shown for ampullosporin A.
- Source: norine
- Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
- Entry information:
- status: curated - change status to non-NRP (Norine validators only)
- last modification date: 2018-12-01 by Emma Ricart Altimiras [Swiss Institute of Bioinformatics, SIB]
- view all entry history
- Type: linear
- Number of monomers: 15
- Smiles: C[C@@H](C(=O)NC(C)(C)C(=O)NC(C)(C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)NC(C)(C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(C)C)CO)NC(=O)[C@H](CCC(=O)N)NC(=O)C(C)(C)NC(=O)[C@H](CC(C)C)NC(=O)C(C)(C)NC(=O)C(C)(C)NC(=O)[C@H](C)NC(=O)[C@H](CC1=CNC2=CC=CC=C21)NC(=O)C
- Graph inference:
- Monomeric composition :
1 Ac-Trp 2 Ala 3 Aib 4 Aib 5 Leu 6 Aib 7 Gln 8 Ala 9 Aib 10 Aib 11 Gln 12 Leu 13 Aib 14 Gln 15 Leuol - Graph representation: Ac-Trp,Ala,Aib,Aib,Leu,Aib,Gln,Ala,Aib,Aib,Gln,Leu,Aib,Gln,Leuol @1 @0,2 @1,3 @2,4 @3,5 @4,6 @5,7 @6,8 @7,9 @8,10 @9,11 @10,12 @11,13 @12,14 @13
- Atomic structure:
- Sepedonium ampullosporum
- taxid: 74838 (view NCBI taxonomy browser)
- Links between organisms producing the ampullosporin B: Sepedonium ampullosporum
- A nonribosomal peptide synthetase involved in the biosynthesis of ampullosporins in Sepedonium ampullosporum
Reiber K, Neuhof T, Ozegowski JH, von Dohrend H, Schwecke T, Journal of peptide science , 2003, Nov-Dec,9(11-12):701-13.
DOI: 10.1002/psc.529
pubMed: 14658790
- Ampullosporins B, C, D, E[1], E[2], E[3] and E[4] from Sepedonium ampullosporum HKI-0053 : Structures and biological activities
Schlegel B, Hartl A, Grafe U, Kronen M, Kleinwachter P, Journal of antibiotics , 2001, vol. 54, no2, pp. 175-178
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