Norine
phakellistatin 10
- Norine ID: NOR00532
- DOI: 10.26097/nor00532
- Family: phakellistatin
- Synonym(s):
phakellistatin 10;
- Activity: antitumor
- Category:
peptide
- Formula: C47H70N9O9
- Monoisotopic mass: 904.529649883 g/mol
- Comment: Phakellistatins are putative NRPS products (no synthetase genes identified)
- Source: norine
- Contributor (creation): Norine Team
[CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
- Entry information:
- Type: cyclic
- Number of monomers: 8
- Smiles: CCC(C)C2NC(=O)C5CCCN5(C(=O)C(NC(=O)C(CC(C)C)NC(=O)C4CCCN4(C(=O)C(NC(=O)C(Cc1ccc(O)cc1)NC(=O)C3CCCN3(C2(=O)))C(C)C))C(C)O)
- Graph inference:
- Monomeric composition :
- Graph representation: Pro,Tyr,Val,Pro,Leu,Thr,Pro,Ile @1,7 @0,2 @1,3 @2,4 @3,5 @4,6 @5,7 @0,6
- Atomic structure:
vizualisation:
- Links between organisms producing the phakellistatin 10: Phakellia sp.
- Antineoplastic agents, 325. Isolation and structure of the human cancer cell growth inhibitory cyclic octapeptides phakellistatin 10 and 11 from Phakellia sp
Pettit GR,
Boyd MR,
Cerny RL,
Doubek DL,
Tackett LP,
Schmidt JM,
Williams MD,
Tan R,
Ichihara Y,
Hooper JN,
Journal of natural products , 1995, Jun,58(6):961-5.
DOI: 10.1021/np50120a025
pubMed: 7673945
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