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phakellistatin 7


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  • Norine ID: NOR00529
  • DOI: 10.26097/nor00529
  • Family: phakellistatin
  • Synonym(s): phakellistatin 7;
  • Activity: antitumor
  • Category: peptide
  • Formula: C59H84N10O11
  • Monoisotopic mass: 1108.63210358 g/mol
  • Comment: Phakellistatins are putative NRPS products (no synthetase genes identified)
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
    • status: putative - change status to non-NRP (Norine validators only)
    • last modification date: 2018-09-12 by Mickael Chevalier [Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
    • view all entry history
  • Type: cyclic
  • Number of monomers: 10
  • Monomeric composition :
    1
    Pro
    2
    Tyr
    3
    Ile
    4
    Pro
    5
    Pro
    6
    Ile
    7
    Phe
    8
    Ala
    9
    Leu
    10
    Pro
  • Graph representation: Pro,Tyr,Ile,Pro,Pro,Ile,Phe,Ala,Leu,Pro @1,9 @0,2 @1,3 @2,4 @3,5 @4,6 @5,7 @6,8 @7,9 @0,8

  • Atomic structure:
  • Peptide's atomic structure image is not available because smiles is not present.

  • Phakellia sp.

  • Links between organisms producing the phakellistatin 7: Phakellia sp.
  • Isolation and structure of the human cancer cell growth inhibitory cyclic decapeptides phakellistatins 7,8 and 9
    Pettit GR, Boyd MR, Cerny RL, Dorsaz AC, Williams MD, Xu JP, Bioorganic and medicinal chemistry letters , 1995, 5 (13), pp. 1339-1344


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