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[des(1-6).Pyr7] alamethicin F30


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  • Norine ID: NOR00013
  • DOI: 10.26097/nor00013
  • Family: alamethicin
  • Synonym(s): [des(1-6).Pyr7] alamethicin F30;
  • Activity: antimicrobial
  • Category: peptaibol
  • Formula: C67H107N15O18
  • Monoisotopic mass: 1409.7918516949999 g/mol
  • Comment: The natural alpha-helical peptide antibiotic alamethicin forms voltage-gated ion channels in lipid membranes.
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
    • status: curated - change status to non-NRP (Norine validators only)
    • last modification date: 2018-09-12 by Mickael Chevalier [Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
    • view all entry history
  • Type: linear
  • Number of monomers: 14
  • Monomeric composition :
    1
    pGlu
    2
    Aib
    3
    Val
    4
    Aib
    5
    Gly
    6
    Leu
    7
    Aib
    8
    Pro
    9
    Val
    10
    Aib
    11
    Aib
    12
    Glu
    13
    Gln
    14
    Pheol
  • Graph representation: pGlu,Aib,Val,Aib,Gly,Leu,Aib,Pro,Val,Aib,Aib,Glu,Gln,Pheol @1 @0,2 @1,3 @2,4 @3,5 @4,6 @5,7 @6,8 @7,9 @8,10 @9,11 @10,12 @11,13 @12

  • Atomic structure:

    • Peptide's atomic structure image is not available because smiles is not present.

  • Trichoderma viride
  • synonyms: Trichoderma lignorum
  • taxid: 5547 (view NCBI taxonomy browser)

  • Links between organisms producing the [des(1-6).Pyr7] alamethicin F30: Trichoderma viride
  • Analysis of the lipophilic peptaibol alamethicin by nonaqueous capillary electrophoresis-electrospray ionization-mass spectrometry
    Psurek A, Neususs C, Pelzing M, Scriba GK, Electrophoresis , 2005, Nov,26(22):4368-78.
    DOI: 10.1002/elps.200500387
    pubMed: 16287177


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