axinastatin 2
- Norine ID: NOR00516
- DOI: 10.26097/nor00516
- Family: axinastatin
- Synonym(s): axinastatin 2;
- Activity: antitumor, toxin
- Category: peptide
- Formula: C39H58N8O8
- Monoisotopic mass: 766.437760872 g/mol
- Comment: axinastatin is a putative NRPS product (no synthetase genes identified)
- Source: norine
- Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
- Entry information:
- status: putative - change status to non-NRP (Norine validators only)
- last modification date: 2018-12-01 by Emma Ricart Altimiras [Swiss Institute of Bioinformatics, SIB]
- view all entry history
- Type: cyclic
- Number of monomers: 7
- Smiles: CC(C)CC2NC(=O)C(NC(=O)C(Cc1ccccc1)NC(=O)C4CCCN4(C(=O)C(CC(N)=O)NC(=O)C(NC(=O)C3CCCN3(C2(=O)))C(C)C))C(C)C
- Graph inference:
- Monomeric composition :
1 Pro 2 Phe 3 Val 4 Leu 5 Pro 6 Val 7 Asn - Graph representation: Pro,Phe,Val,Leu,Pro,Val,Asn @1,6 @0,2 @1,3 @2,4 @3,5 @4,6 @0,5
- Atomic structure:
- Axinella
- taxid: 12958 (view NCBI taxonomy browser)
- Links between organisms producing the axinastatin 2: Axinella
- Antineoplastic agents. 278. Isolation and structure of axinastatins 2 and 3 from a western Caroline Island marine sponge
Pettit GR, Gao F, Cerny RL, Doubek DL, Tackett LP, Schmidt JM, Chapuis JC, Journal of medicinal chemistry , 1994, Apr 15,37(8):1165-8.
DOI: 10.1021/jm00034a014
pubMed: 8164258
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