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discodermin E


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  • Norine ID: NOR00448
  • DOI: 10.26097/nor00448
  • Family: discodermin
  • Synonym(s): discodermin E;
  • Activity: antimicrobial, toxin, antitumor
  • Category: peptide
  • Formula: C76H116N20O21S
  • Monoisotopic mass: 1676.834461574 g/mol
  • Comment: Discodermin A is a putative NRPS product (no synthetase genes identified).
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
    • status: putative - change status to non-NRP (Norine validators only)
    • last modification date: 2018-09-12 by Mickael Chevalier [Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
    • view all entry history
  • Type: partial cyclic
  • Number of monomers: 14
  • Monomeric composition :
    1
    D-NFo-Ala
    2
    Phe
    3
    Pro
    4
    D-t-Leu
    5
    t-Leu
    6
    D-Kyn
    7
    Arg
    8
    D-CysA
    9
    Thr
    10
    NMe-Gln
    11
    D-Leu
    12
    Thr
    13
    Asn
    14
    NMe-Gly
  • Graph representation: D-NFo-Ala,Phe,Pro,D-t-Leu,t-Leu,D-Kyn,Arg,D-CysA,Thr,NMe-Gln,D-Leu,Thr,Asn,NMe-Gly @1 @0,2 @1,3 @2,4 @3,5 @4,6 @5,7 @6,8 @7,9,13 @8,10 @9,11 @10,12 @11,13 @8,12

  • Atomic structure:

    • Peptide's atomic structure image is not available because smiles is not present.

  • Discodermia kiiensis
  • gram:
  • synonyms:
  • taxid: (view NCBI taxonomy browser)

  • Links between organisms producing the discodermin E: Discodermia kiiensis
  • Discodermins F-H, cytotoxic and antimicrobial tetradecapeptides from the marine spone Discodermia kiiensis: Structure revision of discodermins A-D
    Matsunaga S, Fusetani N, Ryu G, Tetrahedron , 1994, 50 (47), pp. 13409-13416


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