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[Gln1]surfactin iC15


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  • Norine ID: NOR00851
  • DOI: 10.26097/nor00851
  • Family: surfactin
  • Synonym(s): [Gln1]surfactin iC15;
  • Activity: antitumor, surfactant
  • Category: lipopeptide
  • Formula: C53H94N8O12
  • Monoisotopic mass: 1034.699120512 g/mol
  • Comment: Isohalobacillin is a mixture of iso and anteiso C15 hydroxy fatty acid.
  • Warning: it has the same structure than lichenysin A iC15
  • Source: norine
  • Contributor (creation): Norine Team [CRIStAL (UMR CNRS 9189), ex-LIFL, France, Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
  • Entry information:
    • status: curated - change status to non-NRP (Norine validators only)
    • last modification date: 2018-09-12 by Mickael Chevalier [Charles Viollette Institute, ProBioGEM team, Lille, France, University of Lille, France]
    • view all entry history
  • Type: cyclic
  • Number of monomers: 8
  • Monomeric composition :
    1
    iC15:0-OH(3)
    2
    Gln
    3
    Leu
    4
    D-Leu
    5
    Val
    6
    Asp
    7
    D-Leu
    8
    Ile
  • Graph representation: iC15:0-OH(3),Gln,Leu,D-Leu,Val,Asp,D-Leu,Ile @1,7 @0,2 @1,3 @2,4 @3,5 @4,6 @5,7 @0,6

  • Atomic structure:

    • Peptide's atomic structure image is not available because smiles is not present.

  • Bacillus subtilis
  • gram: positive
  • synonyms: Bacillus uniflagellatus,Bacillus natto,Bacillus globigii,Vibrio subtilis
  • taxid: 1423 (view NCBI taxonomy browser)

  • Links between organisms producing the [Gln1]surfactin iC15: Bacillus subtilis
  • Inhibition of acyl-CoA: cholesterol acyltransferase by isohalobacillin, a complex of novel cyclic acylpeptides produced by Bacillus sp. A1238
    Park JK, Hasumi K, Endo A, Takizawa K, Takahashi F, The Journal of antibiotics , 1995, Dec,48(12):1419-24.
    DOI: 10.7164/antibiotics.48.1419
    pubMed: 8557597


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